Biography

Eduardo Spinedi completed his Ph. D. degree in Argentina (UNSL), after pre-doctoral trainings at the Department of Physiology, Southwestern Medical School (UTHSCD, Dallas, Tx) and the National Institute of Environmental Health Sciences (NIEHS-NIH, Research Triangle Park, NC). He acted as Assistant Professor at the Neuroendocrine Unit, Geneva University Medical School (1989-1993; Switzerland). He hold a Head-Lab position of the Neuroendocrine Unit at his former institution (IMBICE; 1992-2009). He served as Head-Director at the Centre of Experimental and Applied Endocrinology (CENEXA, UNLP-CONICET, Argentina; 2014-2018) and as Associate Professor of Gynecology (La Plata Medical School; 2014-2019). Actually he is holding the highest researcher position at the Argentina Research Council (CONICET). His actual research area of interest is the interaction between neuroendocrine and adipose tissue functions. He has published (as author/co-author) more than 100 scientific works in highqualified international journals, and is serving as member for several recognized editorial boards, Neuroendocrinology among others.

Research Interest

Diabetes primary prevention program: New insights from data analysis of recruitment period. Gagliardino JJ, Elgart JF, Bourgeois M, Etchegoyen G, Fantuzzi G, Ré M, Ricart JP, García S, Giampieri C, González L, Suárez-Crivaro F, Kronsbein P, Angelini JM, Martínez C, Martínez J, Ricart A, Spinedi E. Diabetes Metab Res Rev. 2018 Jan;34. doi: 10.1002/dmrr.2943. Epub IGF-1 Gene Therapy as a Potentially Useful Therapy for Spontaneous Prolactinomas in Senile Rats. Brown OA, Canatelli-Mallat M, Console GM, Camihort G, Luna G, Spinedi E, Goya RG. Curr Gene Ther. 2018;18:240-245. The Polycystic Ovary Syndrome and the Metabolic Syndrome: A Possible Chronobiotic-Cytoprotective Adjuvant Therapy. Spinedi E, Cardinali DP. Int J Endocrinol. 2018;2018:1349868. N-Acetyl-l-Cysteine treatment efficiently prevented pre-diabetes and inflamed-dysmetabolic liver development in hypothalamic obese rats. Villagarcía HG, Castro MC, Arbelaez LG, Schinella G, Massa ML, Spinedi E, Francini F. Life Sci. 2018;199:88-95. Rejuvenating Effect of Long-Term Insulin-Like Growth Factor-I Gene Therapy in the Hypothalamus of Aged Rats with Dopaminergic Dysfunction. Schwerdt JI, Lopez-Leon M, Cónsole GM, Brown OA, Morel GR, Spinedi E, Goya RG. Rejuvenation Res. 2018;21:102-108. Determinación de marcadores bioquímicos predictivos de enfermedad cardiovascular. Spinedi E. Simposio. XII Congreso FASEN, Mar del Plata EFFECTS OF LACK OF PUBERTAL, OVARY-DEPENDENT PROGRAMMING ON FRUCTOSE INDUCED DYSMETABOLISM. Villagarcía, Hernán Gonzalo., Castro, María Cecilia; Massa, María Laura; Spinedi Eduardo; Francini, Flavio XXV Congreso de la Asociación Latinoamericano para el Estudio del Hígado, ALEH del 20 al 23 de septiembre de 2018 en Punta Cana, República Dominicana. Inducción Síndrome Metabólico por la ovariectomía bilateral en la rata adulta joven: Efecto modulatorio del estradiol sobre el metabolismo lipídico y el estrés oxidativo. Villagarcía HG, Nazar A, Castro MC, Scaglia HE, Massa ML, Spinedi E, Francini F Póster. XXI Congreso Argentino de Diabetes. Mar del Plata, Argentina. Revista de la Sociedad Argentina de Diabetes 52: 52, 2018. La melatonina ejerce efectos benéficos en la rata normal y con Síndrome Metabólico. Pagano E, Varela I, Bertorello B, Padin A, Spinedi E, Genaro A. Póster. L Reunión Anual SAFE 2108, Sociedad Argentina de Farmacología Experimental, Ciudad de Potrero de los Funes, San Luis, Argentina. In vivo and in vitro inhibitory effect of Dexamethasone on the thermogenic process of beige adipocytes . Giordano AP, Zubiría MG, Gambaro SE, Spinedi EJ, Giovambattista A. Presentación Libre. Congreso 2018 de la Sociedad Argentina de Investigación Clínica. Mar del Plata. Buenos Aires, Argentina. Efficacy of metformin therapy to reduce pregnancy-induced hypertensive disorders in women with silent impaired insulin-sensitivity. Romero J, Spinedi E. 2018 Meeting of the European Society of Human Reproductive Endocrinology. Barcelona, España.Póster-626 Neuroendocrine-Metabolic Dysfunction and Sleep Disturbances in Neurodegenerative Disorders: Focus on Alzheimer's Disease and Melatonin. Spinedi E, Cardinali DP. Neuroendocrinology 2018; doi: 10.1159/00 0494889.